19. October 2013 · Comments Off · Categories: Uncategorized

31. August 2013 · Comments Off · Categories: Donate, Event Calendar, News · Tags: ,

Sunday, October 20, 2013

10:30 am – 2:00 pm
Almaden Lake Park
Winfield Blvd & Coleman Avenue (Almaden Expy)
SAN JOSE, CA
 

In 2007, Irene Wing began and coordinated the San Jose WALK FOR A CURE.  She continued in that role until she lost her courageous battle with GIST.  Her friend Liz Chew, in an effort to honor Irene's memory, took over the event and has continued the effort to help erradicate this devastating disease.  

All funds raised go to GCRF to assist in the fight against GIST.  It is the goal of the GCRF to provide patient support, generate awareness for GIST and raise funds to support continued research to expand the development and access of important life-saving therapies. GIST is a cancer that has no cure and afflicts thousands of people annually. With your help, research has helped to prolong and improve the quality of life for those coping with this cancer. We can't do it without you! Thank you for your support!

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03. August 2013 · Comments Off · Categories: Doctor Research

06. June 2013 · Comments Off · Categories: Event Calendar, News · Tags:

Join us to make a difference!!

Help us raise money for local researchers to find a cure for this very rare cancer
Gastro Intestinal Stromal Tumor.
We are having our first Annual Summer Benefit
Come Join us for a fun night @ The Flying W Airport and Resort
Friday July 26th 2013 from 7pm to 11pm.
60 Fostertown Rd. Medford NJ. 08055

The Benefit includes the following:

  •  Open pool with lifeguard so bring bathing suites and the kids
  •  Open bar with beer and wine
  •  Catering provided by Waller’s Deli
  •  Horseshoe pits and Volleyball courts
  •  Live music for all to enjoy
 Hotel rooms are available on site please contact Flying W Airport @ 609-267-8787
We will be holding a Chinese Auction and a 50/50 Raffle.
For ticket information Please Contact Cass Roberts at casper1523@verizon.net or
609-654-2310
All Money Raised will be donated to Gist Cancer Research Fund.
05. June 2013 · Comments Off · Categories: Donate, Event Calendar, In Memory · Tags:

Terri GoembelPlease join us at our fundraiser, in honor of Terri Goembel…

Terri was diagnosed with a cancerous GIST (Gastrointestinal Stromal Tumor) in January 2011. Terri danced her way to heaven on May 9th, 2011.

Please join us in an effort to raise money and awareness for this incurable disease.

During her courageous battle, Terri received over 25 units of blood.  For this reason we encourage you to donate to Memorial Blood Centers. Memorial Blood Centers will be available at the Knights of Columbus Parking lot in a blood mobile. To sign up please visit MBC.ORG/searchdrives, enter #3957.

Following the blood drive…a LARGE silent auction, appetizers & beverages

100% of the proceeds go towards GIST Cancer Research Fund

WHERE:
Knight of Columbus
1114 American Blvd W 
Bloomington, MN 55420

WHEN:
Friday, August 16th

3:30-7PM: BLOOD DRIVE 
7-10PM: FUNDRAISER


TICKETS:
$10.00 per person
Kids are FREE

For more information, contact Trisha Lien at dan_cer2000@hotmail.com

02. June 2013 · Comments Off · Categories: Donate, Event Calendar · Tags:
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28. May 2013 · Comments Off · Categories: Donate, Event Calendar · Tags:

Atlanta Fundraiser

26. May 2013 · Comments Off · Categories: Event Calendar · Tags:

 

In memory of Marie Echavarri

Dodgers Fundraiser

22. May 2013 · Comments Off · Categories: Doctor Research · Tags:

Memorial Sloan-Kettering Cancer Center (MSKCC) is preparing for what it calls “a breakthrough clinical trial” that will test a new drug that uses a MEK inhibitor to target ETV1 in combination with imatinib on a small group of newly diagnosed GIST patients with advanced disease.

We hope to begin recruitment in August, said Dr. William Tap, Section Chief of Sarcoma Oncology at MSKCC. The Phase II trial will be small, with only about 45 participants, and will only have

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one site at MSKCC in New York City, he said. That’s because “we just want to show that this approach works,” before recruiting for a larger scale trial, Dr. Tap said. There will be a Phase I portion of the trial to define the Phase II doses of the combination regimen.

The trial is unique because most new GIST clinical trials recruit patients that already have taken imatinib, sunitinib or other drugs and have already developed resistance to those drugs. This trial will try to show that treatment with a combination of imatinib and the MEK inhibitor from the start will be even more effective in combating GIST and will reduce the likelihood of secondary mutations that cause resistance.

Novartis Pharmaceuticals is co-developing the MEK inhibitor, MEK162, with Array Biopharma. MEK162 has been through Phase I trials and recently completed a Phase II trial in NRAS-mutant melanoma.

Dr. Tap said the research that opened the way to this new approach was led by his colleague at MSKCC, Dr. Ping Chi. She was able to show that ETV1, a transcription factor, was essential to the survival of GIST; while it was hard to target ETV1 because it didn’t have molecule-binding pockets that could be blocked by drugs, she found a way around this problem by discovering that MEK inhibitors could do that job.

“MEK inhibitors alone doesn’t seem to be great, but by doing combination therapy with imatinib we get a dramatic response,” Dr. Chi said. ETV1 is a master regulator that is highly expressed in all GISTS.

“Ping’s discovery is one of the major discoveries that we have seen in GIST research since the discovery of KIT,” Dr. Tap said.


ETV1 inhibitor takes lead in combination approach to clinical trials
Posted by Phil Avila – May 20, 2013 – News, Research
In 2010, Dr. Chi published a study she led, “ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours,” in Nature.

10. May 2013 · Comments Off · Categories: Video

 

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GCRF Meetng OHSU

 

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