31. August 2013 · Comments Off · Categories: Donate, Event Calendar, News · Tags: ,

Sunday, October 20, 2013

10:30 am – 2:00 pm
Almaden Lake Park
Winfield Blvd & Coleman Avenue (Almaden Expy)
SAN JOSE, CA
 

In 2007, Irene Wing began and coordinated the San Jose WALK FOR A CURE.  She continued in that role until she lost her courageous battle with GIST.  Her friend Liz Chew, in an effort to honor Irene's memory, took over the event and has continued the effort to help erradicate this devastating disease.  

All funds raised go to GCRF to assist in the fight against GIST.  It is the goal of the GCRF to provide patient support, generate awareness for GIST and raise funds to support continued research to expand the development and access of important life-saving therapies. GIST is a cancer that has no cure and afflicts thousands of people annually. With your help, research has helped to prolong and improve the quality of life for those coping with this cancer. We can't do it without you! Thank you for your support!

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02. June 2013 · Comments Off · Categories: Donate, Event Calendar · Tags:

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26. May 2013 · Comments Off · Categories: Event Calendar · Tags:

 

In memory of Marie Echavarri

Dodgers Fundraiser

22. May 2013 · Comments Off · Categories: Doctor Research · Tags:

Memorial Sloan-Kettering Cancer Center (MSKCC) is preparing for what it calls “a breakthrough clinical trial” that will test a new drug that uses a MEK inhibitor to target ETV1 in combination with imatinib on a small group of newly diagnosed GIST patients with advanced disease.

We hope to begin recruitment in August, said Dr. William Tap, Section Chief of Sarcoma Oncology at MSKCC. The Phase II trial will be small, with only about 45 participants, and will only have

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one site at MSKCC in New York City, he said. That’s because “we just want to show that this approach works,” before recruiting for a larger scale trial, Dr. Tap said. There will be a Phase I portion of the trial to define the Phase II doses of the combination regimen.

The trial is unique because most new GIST clinical trials recruit patients that already have taken imatinib, sunitinib or other drugs and have already developed resistance to those drugs. This trial will try to show that treatment with a combination of imatinib and the MEK inhibitor from the start will be even more effective in combating GIST and will reduce the likelihood of secondary mutations that cause resistance.

Novartis Pharmaceuticals is co-developing the MEK inhibitor, MEK162, with Array Biopharma. MEK162 has been through Phase I trials and recently completed a Phase II trial in NRAS-mutant melanoma.

Dr. Tap said the research that opened the way to this new approach was led by his colleague at MSKCC, Dr. Ping Chi. She was able to show that ETV1, a transcription factor, was essential to the survival of GIST; while it was hard to target ETV1 because it didn’t have molecule-binding pockets that could be blocked by drugs, she found a way around this problem by discovering that MEK inhibitors could do that job.

“MEK inhibitors alone doesn’t seem to be great, but by doing combination therapy with imatinib we get a dramatic response,” Dr. Chi said. ETV1 is a master regulator that is highly expressed in all GISTS.

“Ping’s discovery is one of the major discoveries that we have seen in GIST research since the discovery of KIT,” Dr. Tap said.


ETV1 inhibitor takes lead in combination approach to clinical trials
Posted by Phil Avila – May 20, 2013 – News, Research
In 2010, Dr. Chi published a study she led, “ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours,” in Nature.

10. May 2013 · Comments Off · Categories: Video

 

Annual

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GCRF Meetng OHSU

      

 

 

 

 

 


You are invited to join us for the annual GCRF Luncheon and Presentation – 

When:

Friday, April 5, 2013

12:00 p.m. to 2:00 p.m.

Where: 

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Fox Chase Cancer Center Reimann Auditorium

333 Cottman Avenue

Philadelphia, PA 19111

RSVP to Wanda Ford, 215.728.3163 or by emailing Wanda.Ford@fccc.edu.

04. January 2013 · Comments Off · Categories: Event Calendar · Tags: ,


The 4th Annual "Walk for A Cure" at Sarg Hubbard Park in Yakima, WA will be held on April 20, 2013   Last year's event

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was a great success. Thanks to all who participated and to all the volunteers who made the event possible.  

There is no fee to register.  Check in at 10 am, walk begins at 11 am.  A light lunch will be served at noon.  All participants are eligible for door prizes and gift baskets.

To register for this year's event, click here to get the current Registration Form.

For more information, contact Tempest Sanborn at Tempsanborn@gmail.com or call her at  Tel: 509-834-8857

For a bit of local coverage of last year's event – click here.

For a copy of the poster, click here.

02. January 2013 · Comments Off · Categories: Donate, Event Calendar · Tags:


Gist RibbonPlease join us for our

5th Annual
Together We Can Make A Difference
GIST
"Find a Cure"
Fund Raiser

Monday, May 6th
at the

View Restaurant

View Restaurant
3 Consuelo Place, Oakdale, NY

Monday, May 6th at 6:30 pm
Admission: $35 per person

Includes hors d'oeuvres, unlimited beer, wine & soda, 50/50 Raffle, Chinese Auction with many exciting items such as:  Dine around Long Island with Gift Cards to many fine restaurants

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…and many more!

Call 631-332-4401 for reservations or e-mail event coordinator Eleanor Svedi at Eleanor@lessings.com

 

Download PDF flier for Event                                             Registration Form/Flyer

01. January 2013 · Comments Off · Categories: Donate, In Memory · Tags: ,

GCRF would like to thank JULIE CRAMER for spearheading another wonderful event.  Held on Feb 23rd  at the Merion, in Cinnaminson, NJ.  This annual event raises money to help eradicate GIST.  Julie began the event to honor the memory of her dad, Mark Becker.

We at GCRF want to thank Julie for a great job well done.  Enjoy the following video, to get a taste of what the evening held…

Watch Video of the Event…



22. November 2012 · Comments Off · Categories: Donate, Event Calendar · Tags:

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